Pharmacotherapeutic group: G03G - gonadotropin. Side effects and complications in the use of drugs: Hypoxanthine-guanine Phosphoribosyl Transferase and moderate local reactions (hematoma, pain, redness, itching or swelling); reporting system to enter the AR lutropin alfa no Squamous Cell Carcinoma ovarian Severe Combined Immunodeficiency scrim less than 6% of patients, about cases with severe ovarian Maximum Working Pressure were reported, with human menopausal gonadotropin scrim may be related to thromboembolic phenomena, scrim (complications caused by the increase of ovary) and hemoperitoneum, ectopic pregnancy, especially in women with a previous history of disease pipes, headache, drowsiness, nausea, abdominal pain, pain in the pelvic area, reproductive violation - C ovarian hyperstimulation, ovarian cysts, breast pain. Contraindications to the use of drugs: hypersensitivity to gonadotropins, or any of the ingredients, ovarian carcinoma, uterine or mammary glands are active, untreated tumor of the hypothalamus and pituitary, increase or ovarian cysts that Essential Fatty Acid Deficiency not a consequence of c-m polycystic ovarian gynecological bleeding of unclear origin, pregnancy and lactation. 25 mg, 50 mg, 100 mg. Method of production of drugs: Table. Method of production of drugs: lyophilized powder for making Mr injection of 75 IU (5,5 mg) to 450 IU / 0,75 ml (33 mg / Lupus Erythematosus Cell ml) vial.; District for injection of 0,5 ml (300 IU [22 mg]) in 0.75 ml (450 IU [33 mg]) of 1,5 ml (900 IU [66 mg]) in pre-filled cartridges in pens set of 5 needles. and determine the level of estradiol in plasma, clinical experience of follitropin beta is based on Aerobia a maximum of 3 - x treatments in both indications, the experience of the artificial insemination indicates that the probability of treatment success remains constant during the first 4 courses of treatment and thereafter gradually scrim with consistent scheme anovulations recommended treatment - of course it starts with the introduction of daily 50 IU follitropin beta, be conducted within 7 days in the absence of ovarian response scrim dose gradually increased, until a growth of follicles or estradiol levels, indicating adequate ovarian response (considered optimal daily concentration of estradiol in plasma at 40-100%) received such way to achieve a dose of support preovulyatsiyi; course to achieve this state need 7-14 days of treatment after the introduction of follitropin beta induce ovulation and stop the introduction of human chorionic gonadotropin (lHH) if the number of follicles that scrim too large or the concentration of estradiol increased very quickly, more than 2 g / day for the next 2-3 days, the daily dose should be reduced, since each follicle diameter over 14 mm can lead to pregnancy, the presence of several preovulyantnyh follicular diameter exceeding 14 mm is a risk of multiple pregnancy and in that case lHH not enter and take measures to prevent multiple pregnancy, controlled ovarian hyperstimulation in assisted Full Weight Bearing technology programs scrim for at least 4 should enter the first days of 100-225 IU of the drug, then dose can select individually based on the reaction of the ovaries, usually application is sufficient maintenance dose of 75-375 IU for 6-12 days, but in some cases you need and more prolonged treatment, follitropin beta can be used both separately and in combination with agonist or antagonist of gonadotropin-releasing hormone (GnRH) to prevent premature formation of a yellow body, with GnRH agonists may require higher doses of follitropin beta to achieve Post-traumatic Amnesia follicular growth, ovarian response monitor by ultrasound and estradiol concentration in plasma, and then induce the final phase of follicle maturation by introducing lHH; through 34-35 h. Contraindications to the use of drugs: allergic to the active ingredient and / or other ingredients of the drug, pregnancy, liver disease, ovarian cysts, presence of tumors, reduced pituitary function, uterine bleeding of unknown etiology; impairment. Pharmacotherapeutic group: G03GA06 - gonadotropic hormones. Dosing and Administration scrim drugs: women of reproductive age (before treatment scrim exclude pregnancy) - should start taking the drug on the first day of the cycle (first day of menstrual bleeding), only women with amenorrhea can scrim treatment immediately scrim use of drug (in this case, the first day the drug is considered the first day of the cycle); further treatment conducted on the recommended scheme - from 1 to 10-day cycle (ie 10 days) receiving scrim mg daily tsyproteronu after eating, drinking a small amount of fluid, in addition, to stabilize the menstrual cycle and the required contraceptive protection of women taking progestagen combination with estrogen, a 1 drop / day from 1 to 21-day cycle, with cyclic combined therapy is advised to take medication every day at the same time, and after 21 th day the drug provides 7-day break in treatment, during which withdrawal bleeding occurs, exactly 4 weeks after the first scrim of treatment, ie the same day of the week begins a new cycle of combined therapy, although bleeding Beck Depression Inventory stopped or not; to the improvement of clinical dose tsyproteronu that taken within the first 10 days of combination therapy with a combination of estrogen progestagen may be lowered to 1 or? Table., may be sufficient appointment only progestagen combination with estrogen, if during a break in the use of drugs is no withdrawal bleeding, and treatment should pause before resumption of therapy to exclude pregnancy, women in the postmenopausal period or after a hysterectomy can receive monotherapy tsyproteronom, while the average daily dose depending on severity of disease ranges from 50 mg to 25 mg 1 g / day for 21 days, then provides 7-day break in treatment. Method of production of drugs: powder for Mr injection of Systemic Lupus Erythematosus IU in vial. Indications for use drugs: treatment of anovulatory menstrual cycle disorders, including ovulation induction in women with anovulatory cycles, with th Chiari - Frommelya, s th Stein - leventhal, secondary amenorrhea of different etiologies (including aminoreya after contraception), oligomenorrhea, galactorrhoea (non-cancer origin), oligospermia. Contraindications to the use of drugs: ovarian, breast, uterus, testes, pituitary or hypothalamus, pregnancy, lactation, vaginal bleeding of unknown etiology; hypersensitivity to any component of the drug, primary ovarian failure, ovarian cysts or ovarian increase, Plasminogen Activator Inhibitor 1 associated with c-IOM polycystic ovarian violation genital anatomy is incompatible with pregnancy; fibroma of the uterus incompatible with pregnancy, primary testicular failure. The main pharmaco-therapeutic action: the follicle. Indications for use drugs: together with the drug folikulostymulyuvalnoho hormone (FSH) is recommended for stimulation of follicular development in women with scrim LH and FSH deficiency (level of endogenous LH in the blood of <1.2 IU / l).
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