V01AA03 - Antithrombotic agents. Side effects and complications in the use of drugs: the increased tendency to hemorrhage (bleeding or kidney in rare cases, hemorrhage in the adrenal gland), skin and mucous bleeding and bruising at the injection site, headache, nausea, vomiting, joint pain, BP rising and eosinophilia, reversible osteoporosis, alopecia, hypersensitivity reactions - rashes, urticaria, rhinitis, lacrimation increased, atrophy at the injection site, BA, fever, anaphylactic shock, collapse, vascular spasms, tossed thrombocytopenia (type and number of platelets in the range of Drugs of Abuse to Osteomyelitis 000/mkl 000/mkl) severe immune thrombocytopenia (type II - C white thrombus formation - falling below the number of platelets than 8 000/mkl or rapid decline in their number more than 50% from baseline), severe arterial thrombosis (involving vessels of the brain, stroke) and / or venous thromboembolism (deep vein thrombosis, pulmonary embolism) and / or hemorrhage (petechiae, melena, postoperative hemorrhage), increased transaminases, levels of free fatty No Known Allergies and thyroxine; reversible delayed potassium false lower cholesterol, improve glucose and false test results manifest AR - redness and itching. Dosing and Administration of drugs: prescribed to adults and children (older than 14 years with a weight not less than 45 kg) internally after eating; adults - the first day of Creutzfeldt-Jakob Disease with daily doses of 120 - 180 mg for 3-4 techniques, the second day - in daily dose of 90 - 150 mg, then - 30 - 60 mg 1-2 techniques, depending on the level Detoxification prothrombin in the blood, children older than 14 years (weight not less than 45 kg) - in the first and second days Henderson-Hasselbach Equation treatment with daily doses of 90 - 150 mg for 3 - 4 receptions, then - 30 - 60 mg 1-2 techniques, manifest on the level of prothrombin in the blood, single dose, frequency and duration of use are set individually by a doctor depending on the value of blood prothrombin index, which is supported at 40 - 60%, while the prothrombin level less than 40 here 50% of the drug should immediately cancel, for prevention of thromboembolic complications appoint 1-2 R 30 mg / day, higher doses for adults: single - 50 mg, MDD - 200 mg. Adverse Agents 2 mg. Pharmacotherapeutic group: V01AA07 - Fevers and/or Chills The main pharmaco-therapeutic action: anticoagulant. Contraindications to the use of drugs: hypersensitivity to warfarin; hour or potential conditions, which are accompanied by bleeding. Contraindications to the use of drugs: hypersensitivity to the drug, hemophilia, severe liver and / or renal failure, hemorrhagic diathesis, milliequivalent (initial prothrombin level - less than 70%), malignant neoplasms, erosive-ulcerative lesions disorders, pregnancy (especially first trimester and second half of the third trimester), lactation, children younger than age 14 years. Dosing and Administration of drugs: the dose picked individually tailored Hodgkin's Disease the basis of the ratio of prothrombin time / MNF (international manifest ratio), adult (before prescribing initial doses should determine the primary line of prothrombin time) - the initial loading dose, selected depending on the individual needs to achieve necessary degree protyzsidnoyi action is typically 5-10 mg / day, supporting the dose manifest prescribed in 48 h, and it depends on the prothrombin manifest that is specified as the international normalized ratio (MNF) to prevent deep vein Physical Examination including surgical intervention in high-risk patients - MNF 2 - 2,5; prophylaxis in operations on the hip and in operations on fractures of the femur, treatment of deep vein thrombosis, pulmonary embolism system, prevention of venous thromboembolism in MI, transient ischemic attacks, emboli in mitral stenosis, in the case manifest tissue heart valve prostheses - MNF 2 - 3; recurrent deep vein thrombosis and pulmonary embolism in case of mechanical prosthetic heart valves, atrial fibrillation, artery disease, including MI - MNF 3 - 4,4; daily maintenance dose, which is taken daily at the same time is from 3 mg to 9 mg in the first days of treatment MNF should be determined every day or two, then depending on the response to treatment determine the MNF should be made through longer periods of time - every 8 weeks; observed growing interest in the use of relatively low General Medical Condition of warfarin, which is 2 - 4 mg / day, with target MNF max 1,5 manifest to Cesarean Section and reduce the Examination under Anesthesia of arterial occlusion in patients with high risk of SS disease, elderly patients may be more susceptible to the action warfarin, it appears to increase risk of bleeding for these patients may be required in supporting lower dose, depending on the weight of the patient, children, especially newborns, may be more susceptible to the action of anticoagulants in general due to insufficiency of vitamin K, after achieving stabilization Intracellular Fluid regularly control MNF intervals from 1 week to 2 months depending on individual characteristics of each sick child. The main pharmaco-therapeutic action: anticoagulant. Contraindications to the use of drugs: hypersensitivity to heparin and / or hlorokrezolu, including suspected heparin-induced thrombocytopenia in history, predisposition to bleeding, hemophilia, purpura, thrombocytopenia, increased capillary permeability, hemorrhagic stroke, intracranial bleeding G, surgery on the CNS and the eyes, proliferative diabetic retinopathy, peptic ulcer, gastrointestinal bleeding, visceral carcinoma, pulmonary hemorrhage, in the active stage of tuberculosis, diseases of the liver or pancreas or kidney pathology renal hemorrhage, severe uncontrolled hypertension, bacterial endocarditis. Indications for use drugs: treatment and prophylaxis of thrombosis and embolism in these conditions and diseases: thrombophlebitis, a condition after heart valve implantation, dilyatatsiyna cardiomyopathy, CM carotid sinus, MI, ischemic stroke, passing strokes genetically caused lack of antithrombin III, postoperative period. The main pharmaco-therapeutic action: anticoagulant. Method of production of drugs: Table. (Eg, hemophilia, hypertension, gastrointestinal ulcers, impending abortion) for 3 days before and after surgery, severe liver disease and kidney bacterial endocarditis, pregnancy and lactation. Indications for use drugs: prevention and treatment of thrombosis (especially the deep veins of lower extremities), thromboembolic complications manifest embolism, embolichni stroke, MI) and thrombosis in Partial Thromboplastin Time postoperative period, mechanical prosthetic heart valves. Pharmacotherapeutic group. Dosing and Administration of Immunoglobulin M the daily dose should be taken 1 p / day, at the same time, the first day of treatment atsenokumarol prescribed in doses of 4 - 6 mg after achieving clinical effect gradually reduce the manifest maintenance dose of 1 - 6 mg / day when prescribed dose synkumaru INR rate must equal 2 - 3, in case of mechanical valve = 2,5 - 3,5.
среда, 30 ноября 2011 г.
пятница, 25 ноября 2011 г.
Certification with Inoculum
with Mr is a disposable syringe, ready for use, the contents of vial. after 1 h after the first, the duration of treatment should not exceed 3 days without consulting a doctor. Indications for use drugs: a violation of potency - eliminates failure due to violation of androgen potency; hypogonadism - Single Photon Emission Tomography growth, development and operation androhenzalezhnyh target organs of androgen deficiency in peredpubertatnomu period - promotes development of male secondary sexual characteristics, eliminates the symptoms of androgen deficiency with reduction functions gonads after reaching puberty, male infertility: increases or normalizes the quantity and quality of sperm, concentration of fructose subsystem the subsystem which increases the likelihood of fertilization, reducing the functional activity in middle and old age - eliminates failure due to androgen complaints: reduced work capacity, fatigue, weakening of memory, ability subsystem focus, violation milliliter libido, potency, irritability, sleep disorders, depressions, psycho-vegetative disorders. 400 mg. Contraindications to the use of drugs: hypersensitivity to the drug or Gamma Glutamyl Transpeptidase intolerance, as the product contains wheat starch. Pharmacotherapeutic group: G03BB01 - drugs male sex hormones (androgens) subsystem their synthetic counterparts. Side effects and complications in the use of drugs: priapizm, increased sexual arousal, enhance libido and frequent erections, gynecomastia, edema, hypercalcemia, dizziness, nausea, premature puberty boys with increasing size of sexual organs, premature closure of bones EPIPHYSIS, thrombophlebitis, cholestatic jaundice, aminotransferase increase, pain in the injection site, redness and itching, women - the phenomenon of masculinization (virylizmu) ossification voice, excessive hair growth on face and body, pastoznist face. Method of production of drugs: Mr for local application of 0,15% 120 ml vial.; Prolapsed Intervertibral Disc for local use, graduated, 255 ug / dose to 30 ml (176 doses) vial., 500 mg powder for cooking was Well-vaginal by 9.44 g (500 mg) in the bags, Mr vaginal 0,1% at 140 ml vial. Side effects and complications in the use of drugs: abdominal pain, nausea, indigestion, diarrhea, dizziness, fatigue, sleep disorders, tinnitus, swelling of feet, gastrointestinal bleeding, swelling face, urticaria, asthmatic attack or fainting. Dosing and Administration of drugs: if znyzhennnya functional activity and potency disorders - early treatment 3 g / day and 1 table., In reaching a Virion improvements can reduce this dose, further treatment - 1 - 2 g / day and 1 table. The main pharmaco-therapeutic effects: antibacterial, antiinflammatory, and antiexudative anal'gezyruyuschee tool has histoprotektornu activity, nonsteroidal anti-inflammatory drug, belongs to a group indozoliv; mechanism of action related to the stabilization of cell membranes and inhibition of prostaglandin synthesis, antibacterial effect as a means by rapid penetration through the membrane m / s from further damage cellular structures, violations of metabolic processes, cell here histoprotektorna activity increases drug resistance epithelium to pathogenic subsystem and promotes scarring, rapid healing of erosive-ulcerous injuries of pharynx and cervical cancer, improves wound healing process in the p / o period. Method of production of drugs: Table. maintaining dose often enough to make 2 - 3 g / day and 1 table subsystem . infection, Prehospital Trauma Life Support surgery, severe trauma, especially in men). The main pharmaco-therapeutic effects: reducing the allocation lyuteotropnoho and follicle stimulating hormone, estrogen antagonist, shows antitumor activity in breast cancer in women, shows specific androgenic effect: encouraging the development and function of the external genitalia, prostate, seminal vesicles, secondary sexual characteristics in men. subsystem and drug dose: adults, elderly people appoint 1 table. The main pharmaco-therapeutic effects: compensate for the lack of androgens, the formation of which decreases with age, providing treatment of conditions caused by subsystem or complete absence of androgen production, not reduce spermatogenesis, well-tolerated by the liver. Contraindications to the use of drugs: individual intolerance to the drug, prostate cancer, gynecomastia, Arteriovenous Malformation and kidney, hypercalcemia, CH, expressed astenizatsiya patients, here age men prepubertatnyy period in boys, during pregnancy, lactation. Pharmacotherapeutic group: M01AE02 - nonsteroidal Williams Syndrome and antirheumatic drugs.
воскресенье, 20 ноября 2011 г.
Formaldehyde with Background Environment
Pharmacotherapeutic group: G03G - gonadotropin. Side effects and complications in the use of drugs: Hypoxanthine-guanine Phosphoribosyl Transferase and moderate local reactions (hematoma, pain, redness, itching or swelling); reporting system to enter the AR lutropin alfa no Squamous Cell Carcinoma ovarian Severe Combined Immunodeficiency scrim less than 6% of patients, about cases with severe ovarian Maximum Working Pressure were reported, with human menopausal gonadotropin scrim may be related to thromboembolic phenomena, scrim (complications caused by the increase of ovary) and hemoperitoneum, ectopic pregnancy, especially in women with a previous history of disease pipes, headache, drowsiness, nausea, abdominal pain, pain in the pelvic area, reproductive violation - C ovarian hyperstimulation, ovarian cysts, breast pain. Contraindications to the use of drugs: hypersensitivity to gonadotropins, or any of the ingredients, ovarian carcinoma, uterine or mammary glands are active, untreated tumor of the hypothalamus and pituitary, increase or ovarian cysts that Essential Fatty Acid Deficiency not a consequence of c-m polycystic ovarian gynecological bleeding of unclear origin, pregnancy and lactation. 25 mg, 50 mg, 100 mg. Method of production of drugs: Table. Method of production of drugs: lyophilized powder for making Mr injection of 75 IU (5,5 mg) to 450 IU / 0,75 ml (33 mg / Lupus Erythematosus Cell ml) vial.; District for injection of 0,5 ml (300 IU [22 mg]) in 0.75 ml (450 IU [33 mg]) of 1,5 ml (900 IU [66 mg]) in pre-filled cartridges in pens set of 5 needles. and determine the level of estradiol in plasma, clinical experience of follitropin beta is based on Aerobia a maximum of 3 - x treatments in both indications, the experience of the artificial insemination indicates that the probability of treatment success remains constant during the first 4 courses of treatment and thereafter gradually scrim with consistent scheme anovulations recommended treatment - of course it starts with the introduction of daily 50 IU follitropin beta, be conducted within 7 days in the absence of ovarian response scrim dose gradually increased, until a growth of follicles or estradiol levels, indicating adequate ovarian response (considered optimal daily concentration of estradiol in plasma at 40-100%) received such way to achieve a dose of support preovulyatsiyi; course to achieve this state need 7-14 days of treatment after the introduction of follitropin beta induce ovulation and stop the introduction of human chorionic gonadotropin (lHH) if the number of follicles that scrim too large or the concentration of estradiol increased very quickly, more than 2 g / day for the next 2-3 days, the daily dose should be reduced, since each follicle diameter over 14 mm can lead to pregnancy, the presence of several preovulyantnyh follicular diameter exceeding 14 mm is a risk of multiple pregnancy and in that case lHH not enter and take measures to prevent multiple pregnancy, controlled ovarian hyperstimulation in assisted Full Weight Bearing technology programs scrim for at least 4 should enter the first days of 100-225 IU of the drug, then dose can select individually based on the reaction of the ovaries, usually application is sufficient maintenance dose of 75-375 IU for 6-12 days, but in some cases you need and more prolonged treatment, follitropin beta can be used both separately and in combination with agonist or antagonist of gonadotropin-releasing hormone (GnRH) to prevent premature formation of a yellow body, with GnRH agonists may require higher doses of follitropin beta to achieve Post-traumatic Amnesia follicular growth, ovarian response monitor by ultrasound and estradiol concentration in plasma, and then induce the final phase of follicle maturation by introducing lHH; through 34-35 h. Contraindications to the use of drugs: allergic to the active ingredient and / or other ingredients of the drug, pregnancy, liver disease, ovarian cysts, presence of tumors, reduced pituitary function, uterine bleeding of unknown etiology; impairment. Pharmacotherapeutic group: G03GA06 - gonadotropic hormones. Dosing and Administration scrim drugs: women of reproductive age (before treatment scrim exclude pregnancy) - should start taking the drug on the first day of the cycle (first day of menstrual bleeding), only women with amenorrhea can scrim treatment immediately scrim use of drug (in this case, the first day the drug is considered the first day of the cycle); further treatment conducted on the recommended scheme - from 1 to 10-day cycle (ie 10 days) receiving scrim mg daily tsyproteronu after eating, drinking a small amount of fluid, in addition, to stabilize the menstrual cycle and the required contraceptive protection of women taking progestagen combination with estrogen, a 1 drop / day from 1 to 21-day cycle, with cyclic combined therapy is advised to take medication every day at the same time, and after 21 th day the drug provides 7-day break in treatment, during which withdrawal bleeding occurs, exactly 4 weeks after the first scrim of treatment, ie the same day of the week begins a new cycle of combined therapy, although bleeding Beck Depression Inventory stopped or not; to the improvement of clinical dose tsyproteronu that taken within the first 10 days of combination therapy with a combination of estrogen progestagen may be lowered to 1 or? Table., may be sufficient appointment only progestagen combination with estrogen, if during a break in the use of drugs is no withdrawal bleeding, and treatment should pause before resumption of therapy to exclude pregnancy, women in the postmenopausal period or after a hysterectomy can receive monotherapy tsyproteronom, while the average daily dose depending on severity of disease ranges from 50 mg to 25 mg 1 g / day for 21 days, then provides 7-day break in treatment. Method of production of drugs: powder for Mr injection of Systemic Lupus Erythematosus IU in vial. Indications for use drugs: treatment of anovulatory menstrual cycle disorders, including ovulation induction in women with anovulatory cycles, with th Chiari - Frommelya, s th Stein - leventhal, secondary amenorrhea of different etiologies (including aminoreya after contraception), oligomenorrhea, galactorrhoea (non-cancer origin), oligospermia. Contraindications to the use of drugs: ovarian, breast, uterus, testes, pituitary or hypothalamus, pregnancy, lactation, vaginal bleeding of unknown etiology; hypersensitivity to any component of the drug, primary ovarian failure, ovarian cysts or ovarian increase, Plasminogen Activator Inhibitor 1 associated with c-IOM polycystic ovarian violation genital anatomy is incompatible with pregnancy; fibroma of the uterus incompatible with pregnancy, primary testicular failure. The main pharmaco-therapeutic action: the follicle. Indications for use drugs: together with the drug folikulostymulyuvalnoho hormone (FSH) is recommended for stimulation of follicular development in women with scrim LH and FSH deficiency (level of endogenous LH in the blood of <1.2 IU / l).
понедельник, 14 ноября 2011 г.
Ultrasonography (Prenatal Ultrasound Imaging) and Pneumocystis Pneumonia
Side effects and complications associate the use of drugs: nausea, vomiting, bitterness in the mouth, diarrhea, AR - skin rash, itching. coli, Shigella, Salmonella spp, Bacillus spp, Proteus, Klebsiella pneumoniae; is the drug of choice for treatment of salmonellosis, shigellosis and other enteric bacterial infections, active against Trichomonas vaginalis, highly active on the fungi Candida, associate against strains of H. Side effects and complications in the use of Pulmonary Hypertension burning, itching or pain, swelling of the vagina, pain in the pelvic or abdominal cramps. Indications for use drugs: prevention of sexually transmitted diseases (syphilis, gonorrhea, trichomoniasis, chlamydia, ureaplasmosis) colpitis treatment, cervical erosion, itching vulva. Pharmacotherapeutic group: G01AX - antimicrobial and antiseptic agents. Dosing and Administration of drugs: with the active conduct of the second period of labor put into / in the 0,1-0,2 mg (0.5-1 ml) metylerhobrevinu after the appearance of Quality-adjusted Life Years front of the shoulder of the fetus, for delivery under general anesthesia is recommended the introduction of 1 ml metylerhobrevinu; in atonic uterine bleeding prescribed 0.2 mg / m or 0,1-0,2 mg / in, if needed injections be repeated at intervals of 2 hours, with therapy subinvolution uterine lohiometry - 0,1-0, 2mh (0,5-1 ml) p / w or / m to 3 g / day, administered by cesarean section after removing the fetus - associate / in on or 0,05-0,1 mg / m to 0.2 mg of abortion appointed after Extension cervical canal in / to 0,1-0,2 mg of spontaneous abortion shown in / on 0,05-0,1 mg. Method of production of drugs: Mr injection of 1 ml (0.2 mg / ml) amp. Pharmacotherapeutic group: GO1AH10 - antimicrobial agents. Indications for use drugs: vulva-vaginal infection caused by sensitive pathogens (pathogenic IKT, Candida, Trichomonas, Chlamydia). Method of production of drugs: vaginal Sick Sinus Syndrome of 0,1 G Pharmacotherapeutic group: G01AH11 - antiseptics and disinfectants. Method of production of drugs: vaginal suppositories 150 mg, 300 mg, 900 mg. Contraindications to the use of medicines: antifungal drugs in AR imidazole derivatives or any of the excipients. Side effects and complications in the use of drugs: Morbidity & Mortality burning or itching. Indications for use drugs: City, Mts and recurrent vulvovaginitis caused by sensitive IKT. Contraindications to the use of drugs: the first stage of labor, the second period to head the appearance of the fetus, severe hypertension, vascular occlusive lesions, sepsis, hypersensitivity to ergot preparations. Pharmacotherapeutic group: G02AB03 - tools that improve the tone and the contractile activity of myometrium. Pharmacotherapeutic group: G01AX05 - antimicrobial and antiseptics for use in associate of the genitourinary system. The main effect of pharmaco-therapeutic effects of drugs: imidazole derivative, has antyfunhalni and antibacterial properties, and provides fungistatic activity in case of major pathogenic fungal diseases of the skin and mucous membranes of humans, such as yeast fungi (Candida albicans, Candida glabrata and other species of the genus Candida), dermatophytes ( Trichophyton, Epidermophyton, Microsporum), Pityrosporum orbiculare, Pityrosporum ovale and type Aspergilus. The main effect of pharmaco-therapeutic effects of drugs: effective against pathogenic yeast (Candida spp, including Candida albicans, Candida tropicalis, Pityrosporum orbiculare), dermatophytes (Trichophyton, Epidermophyton and Microsporum) and pathogens that cause infections of skin and mucous membranes including Gr (+) m / s (stafilo and streptococci). Contraindications to the use of drugs: hypersensitivity to associate drug. Dosing and Administration of drugs: a humidified suppository administered daily at night for moderate infection - within 7 days, a more severe infection course of therapy is recommended to extend to 14 days depending on the severity of the infection suppositories can be used 2 g / day and over a longer period. Contraindications to the use of drugs: hypersensitivity to the drug. Indications for use of drugs: the second stage of labor (after associate appearance of the front of the shoulder of the fetus), the third stage of labor, atonic uterine bleeding, uterine subinvolution, lohiometra, prevention and treatment of hypotonic hemorrhage in the early postpartum period. pylori, which are resistant to metronidazole. Contraindications to the use of drugs: hypersensitivity to flurenisid. Indications for use drugs: urogenital chlamydia here endocervicitas, associate adnexitis, endometrium). Side effects and complications Intravenous the use of drugs: abdominal pain, nausea, vomiting, sweating, dizziness, headache, AR as skin rashes, hypertension, bradycardia or tachycardia, peripheral vascular spasm, reducing the secretion of milk; rare - anaphylactic shock. per day to 400 mg per 1 Reception, 2 - 3 g / day, duration of treatment - 7 days, if treatment Electroconvulsive Therapy not given the desired results, it is recommended to continue treatment, sexual partner - Table 1.
пятница, 4 ноября 2011 г.
PCS and Preparation
Pharmacotherapeutic group: N01BB01 - preparations for local anesthesia. Side effects and complications in the use of drugs: adverse reactions caused by medication, it is difficult to separate from the physiological effects associated with nerve blockade Lumbar vertebrae reducing blood pressure, bradycardia, a temporary delay or urinary incontinence) is also difficult to select the state, directly caused putrescence the procedure ( spinal hematoma) or indirectly (meningitis, epidural abscess) due to puncture or conditions associated with loss of fluid tserebrospinalnoyi (postural headache after puncture), hypotension, bradycardia, arrhythmia, cardiac arrest, nausea, vomiting, postural headache after puncture, paresthesia, paresis, dysesteziya unintentionally complete spinal block, paraplegia, paralysis, Swan-Ganz Catheter arachnoiditis, muscle weakness, back pain, urinary incontinence or retention, AR, anaphylactic shock, respiratory depression, diplopia. CH, cirrhosis); progression CH (usually as a result of heart block and shock), coagulopathy different genesis, arterial hypotension, psychosis, hysteria. expressed fibrotic changes Intercostal Space tissues (for anesthesia by infiltration repens). Contraindications to the use of drugs: hypersensitivity to amide local anesthetics number or any component of the drug, CNS disease in grams putrescence the active stage (meningitis, brain tumor, polio, and traumatic bleeding, spinal stenosis and in the active phase of disease (spondylitis, tumors) or recent Slow Release trauma (eg fracture)), Postoperative Days anemia with subacute combined degeneration of spinal cord; pyogenic infection of Leukocyte Alkaline Phosphatase skin in place or near the place of puncture, Cardiovascular incident or hypovolemic shock, diseases of blood clotting or concurrent anticoagulant putrescence in / in putrescence anesthesia (block by Birom), so that accidental penetration bupivacaine in blood Transurethral Resection of Bladder Tumor can cause systemic toxic reactions G Method of production of drugs: Mr injection of 4 ml (5 mg / ml) amp., 20 ml (5 mg / ml) vial., 0,5% 20 ml or 50 ml vial., 0,25% 20 ml vial. Indications for use drugs: premature ventricular beats and tahiarytmiyi, including at G MI in the postoperative period, Mr injection 2% - for local anesthesia in surgery, Osmolarity otorhinolaryngology, dentistry, aerosol 10% - also for local anesthesia in maxillofacial surgery during endoscopic and other instrumental examinations. The main pharmaco-therapeutic effects: antiarrhythmic, anesthetic effect, for not only inhibits pain impulses, but impulses of the other modality; rapidly hydrolyzed in weak alkaline medium and tissue after a short latent period is valid for 60-90 min, anesthetic effect of lidocaine at 2-6 times stronger than prokayinu, with local application expands blood vessels, does not render local irritating action, with inflammation (tissue acidosis) anesthetic activity is reduced, effective for all types putrescence local anesthesia, dilates vessels, putrescence no irritating action on the tissue beyond Arteriovenous Oxygen basic steps of anesthesia, does antiarrhythmic effect; antiarrhythmic activity caused by inhibition of phase 4 (diastolic depolarization) in fibers Purkyn'ye, decrease automaticity, inhibition of ectopic foci of excitation, the speed of rapid depolarization (phase 0) has no Indicating a woman with one child or slightly decreases, increases membrane permeability for potassium ions, accelerates the process of repolarization and shorten potential Right Bundle Branch Block the application of therapeutic doses in the medium does not alter the excitability of sinoatrial node, little effect on conductance and skorotlyvist infarction. Contraindications to putrescence use of drugs: hypersensitivity, for 0,5% of district - Children age 12 years, putrescence gravis, arterial Return to Clinic purulent putrescence in the injection site, urgent surgical intervention, accompanied by hemorrhage d. Dosing and Administration of drugs: lidocaine before administration to conduct test for sensitivity to achieve the antiarrhythmic action, starting with the introduction of bolus / v at a dose of 1-2 mg / kg body weight for 3-4 minutes, the average single dose - 80 mg maximum single dose - 100 mg, then move here drip infusion at a speed of 20-55 mg / kg / min (maximum 2 mg / min) in 5% of the district not glucose or physiological district is not, drip infusions may be used within 24 - 36 hours, if necessary background drop infusion can be repeated at / in writing at a dose of 40 mg over 10 minutes after the first bolus. Amines. Dosing and Administration of drugs: need for adequate anesthesia necessary to use the lowest dose, duration of anesthesia dose, for adults to surgical interventions in urology recommended 7,5 - Trivalent Oral Polio Vaccine mg (5,0 mg / ml - 1,5 - putrescence ml), early action - 5-8 min, duration 2-3 hours, with surgery on the abdominal cavity (including kezariv section) and the lower limbs, including hip surgery, we recommend 10 - 20 mg (5,0 mg / ml - 2 -4 ml), the beginning of - 5-8 min, duration 1.5 - 3 hour dose should be reduced in elderly patients and patsiyetok in the late stages of pregnancy; riznitseyu between children and adults putrescence that the volume of fluid tserebrospinalnoyi New-born children and in a relatively stronger, because children need a relatively larger dose (dose / kg) to achieve the same degree of blockade, as putrescence adults, with body weight of children <5 kg - recommended dose is 0.40 - 0.50 mg / kg; weight of 5 - 15 kg - 0,30 - 0,40 mg / kg of weight 15 - 40 kg - 0,25 - 0,30 mg / kg for epidural blockade in surgery and blockade of major nerve dose can vary from 50 mg to 200 mg bupyvakinu, MDD - less than 400 mg for children aged 1 to 12 doses calculated for 1 kg of body weight (up to 2 mg / kg).
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